NFL Week 13 best bets, player props, and Thanksgiving Slate predictions. The Degan Doc and Professor Locks break down NFL spreads, totals, and props.
Nothing says “home for the holidays” like five straight days of football and a betting sheet full of action. In this NFL Week 13 Best Bets & Thanksgiving Slate episode, Doc and Professor Locks walk through their favorite player props, sides, totals, and Degen parlays, then close with a full breakdown of the Thanksgiving triple-header.
From Shedeur Sanders’ breakout in Cleveland to the Eagles’ collapse against Dallas, plus strong opinions on Bills–Steelers, Bears–Eagles, Rams–Panthers, Texans–Colts, Bucs–Cardinals, Broncos–Commanders, Giants–Patriots, and the three Thanksgiving games – this one is loaded.
Use this article as your companion to the show: follow along with the timestamps, skim to the matchups you care about most, and plug Doc’s prescriptions into your betting card as you go.
NFL Football Week 13 Episode Breakdown & Timestamps
00:00 – Intro: Home for the Holidays & Week 13 Setup
Doc opens the show by tying Thanksgiving, “wasted Wednesday,” and a massive football stretch together with the Week 13 betting slate.
02:05 – Show Structure Explained
They outline the format: light banter, bye weeks, Week 12 recap, Week 13 props of the week, Doc’s prescriptions (best bets), Degen parlays, and a full Thanksgiving preview.
03:20 – Shedeur Sanders’ Historic First Start
Professor Locks and Doc recap Shedeur Sanders’ first win as Browns QB, how he barely cleared 200 yards, and why the performance was good but not god-tier.
06:10 – Eagles Epic Collapse vs Cowboys
The guys break down the 21–0 start, Dallas’ comeback, and why the Eagles’ offensive line and Lane Johnson’s health are real red flags going forward.
08:35 – What Is ‘Wasted Wednesday’ and Why It Matters
Doc explains the pre-Thanksgiving “wasted Wednesday” tradition and how it sets the tone for five straight days of football and betting.
10:55 – NFL Week 13 Bye Weeks & Schedule Notes
They clarify that Week 13 has no byes, all 32 teams are in action, and Week 14 will bring the final bye week chaos.
11:30 – Week 12 Record Recap
Quick look back: Derek’s heater, Thursday night sweeps, and how the props and sides did overall heading into Week 13.
12:25 – NFL Week 13 Props of the Week
Doc and Professor Locks each deliver three favorite player props, complete with matchup context and recent trends.
25:20 – Doc’s Prescription: Best Bets of the Week
The “Doc’s prescriptions” segment lays out their strongest spread and moneyline plays for the Sunday/Monday slate.
25:40 – Buffalo Bills @ Pittsburgh Steelers
Why Doc is reluctantly fading his own Steelers and backing Josh Allen as a road favorite.
27:38 – Chicago Bears @ Philadelphia Eagles
Deep dive on injuries, trenches, and why Chicago catching a full touchdown is live in Philly.
30:55 – Los Angeles Rams @ Carolina Panthers
Professor Locks makes the case for ugly points with the Panthers as double-digit home dogs vs a traveling Rams team.
33:23 – Houston Texans @ Indianapolis Colts
Doc explains why he’s laying points with a Colts team returning home to the dome after a brutal road stretch.
35:00 – Arizona Cardinals @ Tampa Bay Buccaneers
They both agree Tampa is in a perfect “get-right” spot at home against a worn-down Arizona squad.
38:33 – Denver Broncos @ Washington Commanders
Why Denver’s close wins and conservative offense create value on Washington as a home dog in prime time.
40:50 – New York Giants @ New England Patriots
Doc backs his Giants plus the points, pointing to Patriots’ offensive line injuries and the Giants’ pass rush advantage.
44:10 – BIG Degen Parlays of the Week
Two multi-leg bombs: the ugly backup QB passing-yards parlay and a Lamar/Devon Neal yardage combo with juicy odds.
48:20 – Thanksgiving Football Preview (All Three Games)
The crew shifts into holiday mode and hits all three Thanksgiving games with spreads, totals, and props.
48:55 – Green Bay Packers @ Detroit Lions
Conflicting GB vs DET angles on the total plus props for Jordan Love and Jahmyr Gibbs in a huge NFC North showdown.
55:22 – Kansas City Chiefs @ Dallas Cowboys
A classic Mahomes vs Dak showdown where one side leans Chiefs and the other leans under the big total.
1:00:55 – Cincinnati Bengals @ Baltimore Ravens
Explosive AFC North tilt where both agree: this has shootout written all over it, with monster days for Lamar Jackson and Derrick Henry.
NFL Injury Roundup 🤠
Tuesday, NFL Week 13
Offense#RavensFlock QB Lamar Jackson (toe) – Back to FULL practice after no practice yesterday, as expected. He’ll be good to go for Sunday 📈#WhoDey QB Joe Burrow (toe) – Another FULL participation & expected to start this week 📈…
— Sebastian Fearon DPT, CSCS, OCS (@TheDegenDoc) November 26, 2025
Final Thoughts: Bet Smart, Play Responsibly
Remember to always gamble responsibly and know your limits. If you or someone you know has a gambling problem, call 1-800-GAMBLER.
Thank you for reading my NFL Week 13 – Video Preview. You can read more of my sports betting content on my SG Team Author Page. Feel free to connect with me on X (@MarcSaulino) and follow @StatementGames to stay informed about everything relevant to game day previews.
